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Article

P53 expression is associated with malignant potential in xenograft tissues of a fibrosarcoma mouse model.

Anticancer research - 1 Jan 2000

Skalicky S E, Ow K, Hannan M, Russell P J, Crowe P J, Yang J L

Abstract excerpt

BACKGROUND: The expression of wild-type and mutant p53 was studied in two fibrosarcoma cell lines in a mouse xenograft model. MATERIALS AND METHODS: Human cell lines HT1080 and Hs913(D)T were implanted in athymic mice via intramuscular (i.m.) or subcutaneous (s.c.) routes. After eight weeks, liver, lung and primary inoculation sites were harvested. Sections were stained using two methods: a) haematoxylin and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17465229

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