Article
[Expression of CD44 isoforms in normal human liver and also in regenerative and neoplastic liver changes].
Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 1995
Seelentag W K, Flury R, Schmid M, Komminoth P, Saremaslani P, Günthert U, Heitz P U, Roth J
Abstract excerpt
CD44 is a transmembrane glycoprotein of which a large number of isoforms exist. There is evidence, mostly from experimental systems, that isoforms of CD44 generated by alternative splicing of ten variant exons are involved in tumor invasion and metastasis formation. We have evaluated the expression of CD44 standard (CD44s) and variant exons (CD44v) encoded gene products in formalin-fixed and paraffin-embedded...
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