The variant mRNA isoform of human metastasis gene (CD44V) detected in the cell lines of human hepatocellular carcinoma.

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Article

The variant mRNA isoform of human metastasis gene (CD44V) detected in the cell lines of human hepatocellular carcinoma.

Biochemistry and molecular biology international - 1 Feb 1994

Harn H J, Ho L I, Yu C P, Wang M W, Lee H S, Lin J J, Lee W H, Isola N R, Cooper D L

Abstract excerpt

The interaction of the cell surface receptor CD44 molecular with its ligands (addressin, extracellular matrix etc.,) plays an important role in fulfilling the lymphocyte homing and immune reaction. Recently alternatively spliced products of CD44 gene are found to be involved in tumor metastasis as well. Our report found that CD44 prototype RNA (CD44S) was present in all five tumor cell lines. Isoform CD44 RNA...

Topics

Base Sequence
Carcinoma, Hepatocellular
Carrier Proteins
DNA, Neoplasm
Exons
Genetic Variation
Humans
Hyaluronan Receptors
Isomerism
Liver Neoplasms
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Metastasis

Neoplastic Cells, Circulating

Phenotype

RNA, Messenger

Receptors, Cell Surface

Receptors, Lymphocyte Homing

Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 7517252

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7517252-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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