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Article

Control of HPV 18 DNA replication by cellular and viral transcription factors.

Nucleic acids research - 11 Dec 1995

Demeret C, Le Moal M, Yaniv M, Thierry F

Abstract excerpt

Papillomavirus replication in vivo requires the interaction of the virally encoded proteins E1 and E2 with the origin of replication which is localised in the regulatory region (long control region or LCR) of the viral genome. In genital human papillomaviruses (HPVs), the origin overlaps promoter elements of early transcription. In this study, we analysed the replication of HPV18 DNA using the complete LCR...

Topics

Adenovirus E2 Proteins
Base Sequence
Binding Sites
DNA Replication
Humans
Molecular Sequence Data
Mutation
Papillomaviridae
Promoter Regions, Genetic
Sp1 Transcription Factor
Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virus Replication

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Identifiers

PMID: 8532518
DOI: 10.1093/nar/23.23.4777
PMCID: PMC307464

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