Article
Phosphorylation of the 26 kDa TNF precursor in monocytic cells and in transfected HeLa cells.
Journal of inflammation - 1 Jan 1995
Pócsik E, Duda E, Wallach D
Abstract excerpt
Tumor necrosis factor (TNF) functions both as a soluble molecule and as a cell surface 26 kDa transmembrane protein, from which the soluble form is proteolytically derived. The 26 kDa TNF molecules isolated from 32P labeled HeLa cells that had been transfected with the cDNA of a partially cleavable TNF mutant were found labeled. Phosphorylated 26 kDa TNF molecules could also be isolated from human LPS stimulated...
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