Article
Altered sensory processing in the somatosensory cortex of the mouse mutant barrelless.
Science (New York, N.Y.) - 29 Mar 1996
Welker E, Armstrong-James M, Bronchti G, Ourednik W, Gheorghita-Baechler F, Dubois R, Guernsey D L, Van der Loos H, Neumann P E
Abstract excerpt
Mice homozygous for the barrelless (brl) mutation, mapped here to chromosome 11, lack barrel-shaped arrays of cell clusters termed "barrels" in the primary somatosensory cortex. Deoxyglucose uptake demonstrated that the topology of the cortical whisker representation is nevertheless preserved. Anterograde tracers revealed a lack of spatial segregation of thalamic afferents into individual barrel territories, and...
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