Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation of CA dinucleotide repeats close to D6S105; linkage disequilibrium with haemochromatosis.

Human molecular genetics - 1 Nov 1994

Stone C, Pointon J J, Jazwinska E C, Halliday J W, Powell L W, Robson K J, Monaco A P, Weatherall D J

Abstract excerpt

The gene for hereditary haemochromatosis (HC) is linked to HLA-A and D6S105 on chromosome 6p. Both markers have also been reported to display linkage disequilibrium with the disease. However, their physical localization relative to one another has not been established. We demonstrate by fluorescent in situ hybridisation that D6S105 lies at least 1-2 Mb telomeric of HLA-A. The haemochromatosis critical region...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to Hemochromatosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Linkage Disequilibrium

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Share to Repetitive Sequences, Nucleic Acid

Source

Identifiers

PMID: 7874124

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Isolation of CA dinucleotide repeats close to D6S105; linkage disequilibrium with haemochromatosis.PMID 7874124Read ↗

Localization of the hemochromatosis gene close to D6S105.Semantic proximity Read ↗

New polymorphic microsatellite markers place the haemochromatosis gene telomeric to D6S105.Semantic proximity Read ↗

Allelic association of microsatellites of 6p in Italian hemochromatosis patients.Semantic proximity Read ↗

A new highly polymorphic marker in the 5' untranslated region of HLA-F shows strong allelic association with haemochromatosis.Semantic proximity Read ↗

A putative gene located at the MHC class I region around the D6S105 marker contributes to the setting of CD8+ T-lymphocyte numbers in humans.Semantic proximity Read ↗

Anonymous marker loci within 400 kb of HLA-A generate haplotypes in linkage disequilibrium with the hemochromatosis gene (HFE)Semantic proximity Read ↗

Haplotype analysis in Australian hemochromatosis patients: evidence for a predominant ancestral haplotype exclusively associated with hemochromatosis.Semantic proximity Read ↗

Allelic associations and homozygosity at loci from HLA-B to D6S299 in genetic haemochromatosis.Semantic proximity Read ↗

A polymorphic DNA marker at the D10S106 locus.Semantic proximity Read ↗

The frequency of the haemochromatosis-associated genotype D6S265-1:D6S105-8 in blood donors.Semantic proximity Read ↗

Linkage disequilibrium analysis of Friedreich's ataxia in 140 Caucasian families: positioning of the disease locus and evaluation of allelic heterogeneity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.