Article
Isolation of CA dinucleotide repeats close to D6S105; linkage disequilibrium with haemochromatosis.
Human molecular genetics - 1 Nov 1994
Stone C, Pointon J J, Jazwinska E C, Halliday J W, Powell L W, Robson K J, Monaco A P, Weatherall D J
Abstract excerpt
The gene for hereditary haemochromatosis (HC) is linked to HLA-A and D6S105 on chromosome 6p. Both markers have also been reported to display linkage disequilibrium with the disease. However, their physical localization relative to one another has not been established. We demonstrate by fluoresce...
Topics
- Alleles
- Base Sequence
- Hemochromatosis
- Humans
- In Situ Hybridization, Fluorescence
- Linkage Disequilibrium
- Molecular Sequence Data
- Polymerase Chain Reaction
- Repetitive Sequences, Nucleic Acid