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Article

Cytotoxic Compounds from a Two-Sponge Association

1 Nov 1995

Abstract excerpt

Investigation of the cytotoxic constituents of a two-sponge association (Poecillastra sp. and Jaspis sp.) led to the isolation of pectenotoxin II [1] and psammaplin A as the active compounds. In an in vitro cell culture assay, 1 displayed very potent cytotoxic activities against human lung (A-549), colon (HT-29), and breast (MCF-7) cancer cell lines. Pectenotoxin II also exhibited selective cytotoxicity against...

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Identifiers

PMID: 8594149
DOI: 10.1021/np50125a012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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