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Structural elucidation, total synthesis, and cytotoxic activity of effphenol A

1 Jan 2020

Abstract excerpt

A highly substituted phenol derivative, effphenol A (1), was isolated from the deep-sea-derived fungus Trichobotrys effuse FS524. Its complete structural assignment was established through a combination of spectroscopic analysis together with single-crystal X-ray diffraction experiments and further unequivocally confirmed by a biomimetic total synthesis. Structurally, effphenol A possesses a poly-substituted...

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PMID: 33135037
DOI: 10.1039/d0ob01985b

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