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Article

Potent Cytotoxic Peptides from the Australian Marine Sponge Pipestela candelabra

4 Jun 2014

Abstract excerpt

Two consecutive prefractionated fractions of the Australian marine sponge extract, Pipestela candelabra, were identified to be selectively active on the human prostate cancer cells (PC3) compared to the human neonatal foreskin fibroblast non-cancer cells (NFF). Twelve secondary metabolites were isolated in which four compounds are new small peptides. Their structures were characterized by spectroscopic and...

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PMID: 24901701
DOI: 10.3390/md12063399

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