Article
Overshooting production of satellite cells in murine skeletal muscle affected by the mutation "muscular dystrophy with myositis" (mdm, Chr 2).
Cell and tissue research - 1 Mar 1996
Heimann P, Menke A, Rothkegel B, Jockusch H
Abstract excerpt
The hereditary degenerative muscle disease "muscular dystrophy with myositis" of the mouse (MDM, genotype mdm/mdm) is caused by a spontaneous recessive mutation on chromosome 2. Skeletal muscles of MDM mice degenerate during the first few postnatal weeks and subsequently regenerate. The cellular and molecular mechanisms of this muscle disease are not yet understood. An inflammatory component as implied by its...
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