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Article

Satellite cells deficiency and defective regeneration in dynamin 2-related centronuclear myopathy.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Apr 2021

F Almeida Camila, Bitoun Marc, Vainzof Mariz

Abstract excerpt

Dynamin 2 (DNM2) is a ubiquitously expressed protein involved in many functions related to trafficking and remodeling of membranes and cytoskeleton dynamics. Mutations in the DNM2 gene cause the autosomal dominant centronuclear myopathy (AD-CNM), characterized mainly by muscle weakness and central nuclei. Several defects have been identified in the KI-Dnm2R465W/+ mouse model of the disease to explain the muscle...

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Share to Dynamin II
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knock-In Techniques

Share to Muscle, Skeletal

Share to Myogenic Regulatory Factors

Share to Myopathies, Structural, Congenital

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Share to Satellite Cells, Skeletal Muscle

Source

Identifiers

PMID: 33715228
DOI: 10.1096/fj.202001313RRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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