Article
Inducible NorA-mediated multidrug resistance in Staphylococcus aureus.
Antimicrobial agents and chemotherapy - 1 Dec 1995
Kaatz G W, Seo S M
Abstract excerpt
The NorA protein of Staphylococcus aureus mediates the active efflux of hydrophilic fluoroquinolones from the cell, conferring low-level resistance upon the organism. The protein also is capable of transporting additional structurally diverse compounds, indicating that it has a broad substrate specificity. Increased transcription of the norA gene, leading to a greater quantity of the NorA protein within the...
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