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Analysis of chromosome behavior in intact mammalian oocytes: monitoring the segregation of a univalent chromosome during female meiosis

1 Nov 1995

Abstract excerpt

To monitor the behavior of specific chromosomes at various stages of mammalian female meiosis, we have combined immunofluorescence staining and fluorescence in situ hybridization (FISH) on intact oocytes. We have utilized this technique to evaluate the behavior of the single X chromosome in oocytes from XO female mice, providing the first observations on segregation of an achiasmate chromosome during mammalian...

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PMID: 8589675
DOI: 10.1093/hmg/4.11.2007

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