Article
Linkage between stature and a region on chromosome 20 and analysis of a candidate gene, bone morphogenetic protein 2.
American journal of medical genetics - 4 Dec 1995
Thompson D B, Ossowski V, Janssen R C, Knowler W C, Bogardus C
Abstract excerpt
Sib-pair linkage analysis of the quantitative trait, structure, in over 500 Pima Indians indicates that a genetic determinant of governing stature is located on chromosome 20. Analysis of 10 short tandem repeat polymorphisms localized this linkage to a 3.2cM region that includes D20S98 and D20S66. Using all possible sib-pair combinations, linkage was detected to both stature (P = 0.0001) and to leg length (P =...
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