Article
A region of chromosome 20 is linked to leprosy susceptibility in a South Indian population.
The Journal of infectious diseases - 15 Oct 2002
Tosh Kerrie, Meisner Sarah, Siddiqui M Ruby, Balakrishnan Karuppiah, Ghei Satish, Golding Marina, Sengupta Utpal, Pitchappan Ramasamy M, Hill Adrian V S
Abstract excerpt
A major susceptibility locus for leprosy has recently been mapped on chromosome 10 (10p13) by genome-wide linkage analysis. Microsatellite markers from this genome screen that showed suggestive evidence of linkage to leprosy were evaluated in an additional 140 families with affected sib pairs. A second region of linkage has thus been identified on chromosome 20 (20p12). The peak of linkage lies at marker D20S115,...
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