Article
Roles of ABF1, NPL3, and YCL54 in silencing in Saccharomyces cerevisiae.
Genetics - 1 Nov 1995
Loo S, Laurenson P, Foss M, Dillin A, Rine J
Abstract excerpt
A sensitized genetic screen was carried out to identify essential genes involved in silencing in Saccharomyces cerevisiae. This screen identified temperature-sensitive alleles of ORC2 and ORC5, as described elsewhere, and ABF1, NPL3, and YCL54, as described here. Alleles of ABF1 that caused silencing defects provided the genetic proof of Abflp's role in silencing. The roles of Npl3p and Ycl54p are less clear....
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