Article
CWH41 encodes a novel endoplasmic reticulum membrane N-glycoprotein involved in beta 1,6-glucan assembly.
Journal of bacteriology - 1 Feb 1996
Jiang B, Sheraton J, Ram A F, Dijkgraaf G J, Klis F M, Bussey H
Abstract excerpt
CWH41 encodes a novel type II integral membrane N-glycoprotein located in the endoplasmic reticulum. Disruption of the CWH41 gene leads to a K1 killer toxin-resistant phenotype and a 50% reduction in the cell wall beta 1,6-glucan level. CWH41 also displays strong genetic interactions with KRE1 an...
Topics
- Amino Acid Sequence
- Base Sequence
- Blotting, Western
- Cell Compartmentation
- Cell Wall
- Cloning, Molecular
- Crosses, Genetic
- Drug Resistance, Microbial
- Endoplasmic Reticulum
- Fungal Proteins
- Genes, Fungal
- Glucans
- Glycoproteins
- Killer Factors, Yeast
- Membrane Glycoproteins
- Membrane Proteins
- Molecular Sequence Data
- Mutation