Article
Effect of signal peptide alterations and replacement on export of xylanase A in Streptomyces lividans.
Applied and environmental microbiology - 1 Jan 1996
Pagé N, Kluepfel D, Shareck F, Morosoli R
Abstract excerpt
Starting from its translation initiation site, the Streptomyces lividans xylanase A signal peptide consists of 41 amino acids. This signal peptide was deleted and successively replaced with one of six signal peptides from other enzymes secreted by S. lividans and by a signal peptide from the outer membrane protein (LamB) of Escherichia coli. Deletion of the xylanase A signal peptide or modification of its...
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