Article
Exploring the Feasibility of the Sec Route to Secrete Proteins Using the Tat Route in Streptomyces lividans.
Molecular biotechnology - 1 Oct 2015
Gullón Sonia, Vicente Rebeca L, Valverde José R, Marín Silvia, Mellado Rafael P
Abstract excerpt
Streptomyces lividans uses mainly two pathways to target secretory proteins to the cytoplasmic membrane. The major pathway (Sec pathway) transports pre-proteins using the signal recognition particle, and the minor Tat pathway is responsible for the secretion using a folded conformation of a relatively low number of proteins. The signal peptides of the Sec-dependent alpha-amylase and the Tat-dependent agarase were...
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