Article
The twin-arginine translocation pathway is a major route of protein export in Streptomyces coelicolor.
Proceedings of the National Academy of Sciences of the United States of America - 21 Nov 2006
Widdick David A, Dilks Kieran, Chandra Govind, Bottrill Andrew, Naldrett Mike, Pohlschröder Mechthild, Palmer Tracy
Abstract excerpt
The twin-arginine translocation (Tat) pathway is a protein transport system for the export of folded proteins. Substrate proteins are targeted to the Tat translocase by N-terminal signal peptides harboring a distinctive R-R-x-Phi-Phi "twin-arginine" amino acid motif. Using a combination of proteomic techniques, the protein contents from the cell wall of the model Gram-positive bacterium Streptomyces coelicolor...
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