Article
Influence of HLA-DR phenotype on tumor necrosis factor-alpha production in renal-transplant recipients.
Nephron - 1 Jan 1995
Peces R, Urra J M, de la Torre M
Abstract excerpt
In healthy subjects, previous studies have demonstrated a great interindividual variability in the ability for tumor necrosis factor-alpha (TNF-alpha) production. The gene for TNF-alpha is closely linked to and located in the major histocompatibility complex (MHC) and it has been suggested that these interindividual differences may be HLA related. Since TNF-alpha is likely to be an important mediator in renal...
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