Article
Impaired kidney graft survival is associated with the TNF-alpha genotype.
Transplantation - 15 Jul 2004
Wramner Lars G, Norrby Jonny, Hahn-Zoric Mirjana, Ahlmén Jarl, Börjesson Per-Anders, Carlström Jan, Hytönen Anne-Marie, Olausson Michael, Hanson Lars A, Padyukov Leonid
Abstract excerpt
BACKGROUND: The TNF2 allele at position -308 of the tumor necrosis factor (TNF)-alpha gene is associated with high TNF production. The purpose was to study the association of this gene polymorphism with rejection episodes and graft survival after kidney transplantation. METHODS: A retrospective analysis of transplant outcomes of patients who only had been treated with one single form of immunosuppression...
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