Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for a genetic predisposition towards acute rejection after kidney and simultaneous kidney-pancreas transplantation.

Transplantation - 27 Aug 2000

Pelletier R, Pravica V, Perrey C, Xia D, Ferguson R M, Hutchinson I, Orosz C

Abstract excerpt

BACKGROUND: In vitro production of tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), interleukin 10 (IL-10), and transforming growth factor-beta (TGF-beta) correlate with their respective genetic polymorphisms. We analyzed the relationship between these genetic polymorphisms and posttransplant outcome. METHODS: Using DNA polymerase chain reaction (PCR) technology, polymorphisms for TNF-alpha,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to Drug Therapy, Combination

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Graft Rejection

Share to Immunosuppressive Agents

Share to Interferon-gamma

Share to Interleukin-10

Share to Kidney Transplantation

Share to Transforming Growth Factor beta

Source

Identifiers

PMID: 10972228
DOI: 10.1097/00007890-200008270-00023

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for a genetic predisposition towards acute rejection after kidney and simultaneous kidney-pancreas transplantation.PMID 10972228Read ↗

Cytokine gene polymorphisms predict acute graft rejection following renal transplantation.Semantic proximity Read ↗

Cytokine Gene Polymorphisms and Risks of Acute Rejection and Delayed Graft Function after Kidney TransplantationSemantic proximity Read ↗

Influence of recipient and donor IL-10, TNFA and INFG genotypes on the incidence of acute renal allograft rejection.Semantic proximity Read ↗

Contribution of TNF-α and IL-10 gene polymorphisms to graft-versus-host disease following allo-hematopoietic stem cell transplantationSemantic proximity Read ↗

Cytokine gene polymorphism and heart transplant rejection.Semantic proximity Read ↗

Cytokine gene polymorphisms in kidney transplantation.Semantic proximity Read ↗

Renal allograft immune response is influenced by patient and donor cytokine genotypes.Semantic proximity Read ↗

TNF-alpha, IL-6, IFN-gamma, and IL-10 gene expression polymorphisms and the IL-4 receptor alpha-chain variant Q576R: effects on renal allograft outcome.Semantic proximity Read ↗

Association of polymorphisms in the human interferon-gamma and interleukin-10 gene with acute and chronic kidney transplant outcome: the cytokine effect on transplantation.Semantic proximity Read ↗

Impact of donor and recipient cytokine genotypes on renal allograft outcome.Semantic proximity Read ↗

Donor cytokine genotype influences the development of acute rejection after renal transplantation.Semantic proximity Read ↗

Study of the cytokine polymorphisms in correlation to rejection and graft survival in renal allograft donors and recipients from a homogenous Saudi population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.