Article
A genetic marker of high TNF-alpha production in heart transplant recipients.
Transplantation - 27 Nov 1995
Turner D M, Grant S C, Lamb W R, Brenchley P E, Dyer P A, Sinnott P J, Hutchinson I V
Abstract excerpt
The cytokine TNF-alpha has been implicated in the pathogenesis of both acute and chronic transplant rejection. Levels of the cytokine are known to vary in a normal population, leading to speculation that high responders may be at greater risk of rejection. Particular TNF region polymorphic marker...
Topics
- Alleles
- DNA, Satellite
- Genetic Markers
- Heart Transplantation
- Humans
- Mutation
- Pilot Projects
- Tumor Necrosis Factor-alpha