Article
The timing of emergence of muscle progenitors is controlled by an FGF/ERK/SNAIL1 pathway.
Developmental biology - 15 Sept 2009
Delfini Marie-Claire, De La Celle Marie, Gros Jérome, Serralbo Olivier, Marics Irène, Seux Mylène, Scaal Martin, Marcelle Christophe
Abstract excerpt
In amniotes, the dermomyotome is the source of all skeletal muscles of the trunk and the limbs. Trunk skeletal muscles form in two sequential stages: in the first stage, cells located at the four borders of the epithelial dermomyotome delaminate to generate the primary myotome, composed of post-mitotic, mononucleated myocytes. The epithelio-mesenchymal transition (EMT) of the central dermomyotome initiates the...
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