Article
Clonal analysis of CD4 mediated accessory function on the effector activity of human CD4+ T cell subsets.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Sept 1995
Lamb J R, Faith A, Higgins J A, Verhoef A, Schneider P, Yssel H, O'Hehir R E
Abstract excerpt
BACKGROUND: It has been reported for the peripheral T cell repertoire that CD4 molecules may enhance adhesion between T cells and antigen presenting cells and, through their physical association with T cell antigen receptors, contribute to signal transduction. OBJECTIVE: The aims of this study were to determine if the modulation of CD4 molecules had differential effects on T cell recognition, antigen induced...
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