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Article

Thymine auxotrophy as an attenuating marker in Vibrio cholerae.

Microbial pathogenesis - 1 Jul 1995

Attridge S R

Abstract excerpt

Vibrio cholerae CVD102 is a thymine-dependent auxotroph of CVD101, a cholera toxin A-B+ candidate live oral cholera vaccine. Previous clinical experience with these strains suggested that, by restricting intestinal growth, thymine auxotrophy is attenuating for V. cholerae. Studies in the infant m...

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Identifiers

PMID: 8559036
DOI: 10.1006/mpat.1995.0040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8559036-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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