Article
Abrogation of the twin arginine transport system in Salmonella enterica serovar Typhimurium leads to colonization defects during infection.
PloS one - 26 Jan 2011
Reynolds M Megan, Bogomolnaya Lydia, Guo Jinbai, Aldrich Lindsay, Bokhari Danial, Santiviago Carlos A, McClelland Michael, Andrews-Polymenis Helene
Abstract excerpt
TatC (STM3975) is a highly conserved component of the Twin Arginine Transport (Tat) systems that is required for transport of folded proteins across the inner membrane in gram-negative bacteria. We previously identified a ΔtatC mutant as defective in competitive infections with wild type ATCC14028 during systemic infection of Salmonella-susceptible BALB/c mice. Here we confirm these results and show that the...
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