Article
Rapid genotyping of low density lipoprotein receptor knockout mice using a polymerase chain reaction technique.
Laboratory animals - 1 Oct 1995
Gaw A, Mancini F P, Ishibashi S
Abstract excerpt
A new method for the rapid genotyping of low density lipoprotein receptor knockout mice is described. This method using a polymerase chain reaction (PCR) technique may be performed on small tissue biopsies, and represents a significant advantage in time over conventional genotyping by Southern bl...
Topics
- Animals
- Base Sequence
- Blotting, Southern
- DNA
- Disease Models, Animal
- Genotype
- Hyperlipoproteinemia Type II
- Mice
- Mice, Knockout
- Molecular Sequence Data
- Polymerase Chain Reaction
- Receptors, LDL
