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A rapid method for genotyping mice for T cell receptor V beta a and V beta b haplotypes by PCR analysis of whole blood.

Journal of immunological methods - 31 Dec 1990

Spinella D G

Abstract excerpt

Strains of laboratory mice bearing a germline deletion of some T cell receptor V beta genes have proven useful in a variety of studies of T cell receptor function. Analysis of genetic crosses between deleted and wild type strains can provide information about the relevance of genes located within the deletion to specific T cell responses. Existing techniques for genotyping offspring of such crosses usually...

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PMID: 1980283
DOI: 10.1016/0022-1759(90)90274-y

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