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Article

A rapid method for genotyping mice for T cell receptor V beta a and V beta b haplotypes by PCR analysis of whole blood.

Journal of immunological methods - 31 Dec 1990

Spinella D G

Abstract excerpt

Strains of laboratory mice bearing a germline deletion of some T cell receptor V beta genes have proven useful in a variety of studies of T cell receptor function. Analysis of genetic crosses between deleted and wild type strains can provide information about the relevance of genes located within the deletion to specific T cell responses. Existing techniques for genotyping offspring of such crosses usually...

Topics

Animals
Base Sequence
Blood
DNA
Electrophoresis, Agar Gel
Genetic Techniques
Genotype
Haplotypes
Mice
Mice, Inbred DBA
Mice, Inbred Strains
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Receptors, Antigen, T-Cell

Restriction Mapping

Source

Identifiers

PMID: 1980283
DOI: 10.1016/0022-1759(90)90274-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1980283-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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