Article
A novel technique for rapid automated genotyping of DNA polymorphisms in the mouse.
Molecular and cellular probes - 1 Jun 1999
Kuklin A, Davis A P, Hecker K H, Gjerde D T, Taylor P D
Abstract excerpt
The ability to rapidly and reliably genotype mice is an important concern. Traditional methods employ labour intensive and time consuming techniques such as test crossing, gel electrophoresis or nucleic acid hybridization. Here we show that a new molecular biology workstation, the WAVE DNA Fragment Analysis System, can easily resolve polymerase chain reaction (PCR) products that have small differences in their...
Topics
- Animals
- Automation
- DNA
- Genotype
- Mice
- Polymorphism, Genetic
- Time Factors