Article
Erratic G-->A hypermutation within a complete caprine arthritis-encephalitis virus (CAEV) provirus.
Virology - 1 Jun 1995
Wain-Hobson S, Sonigo P, Guyader M, Gazit A, Henry M
Abstract excerpt
The complete nucleotide sequence of an integrated provirus of caprine arthritis-encephalitis virus (CAEV) has been determined. The provirus was defective due to extensive G-->A hypermutation. Rather than being a smooth phenomenon distributed throughout the genome it was highly erratic with hypermutated and normal regions being juxtaposed, probably reflecting local fluctuations in the intracellular dCTP pool...
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