Article
Erratic G-->A hypermutation within a complete caprine arthritis-encephalitis virus (CAEV) provirus.
Virology - 1 Jun 1995
Wain-Hobson S, Sonigo P, Guyader M, Gazit A, Henry M
Abstract excerpt
The complete nucleotide sequence of an integrated provirus of caprine arthritis-encephalitis virus (CAEV) has been determined. The provirus was defective due to extensive G-->A hypermutation. Rather than being a smooth phenomenon distributed throughout the genome it was highly erratic with hyperm...
Topics
- Adenine
- Amino Acid Sequence
- Animals
- Arthritis-Encephalitis Virus, Caprine
- Base Sequence
- Cloning, Molecular
- DNA Primers
- Gene Products, env
- Gene Products, rev
- Genes, pol
- Genetic Variation
- Genome, Viral
- Goats
- Guanine
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Protein Sorting Signals