Article
The role of retroviral dUTPases in replication and virulence.
Current protein & peptide science - 1 Dec 2001
Payne S L, Elder J H
Abstract excerpt
Several retroviruses, including equine infectious anemia virus (EIAV), visna virus, caprine arthritis-encephalitis virus (CAEV) and feline immunodeficiency virus (FIV) encode dUTPase. The role of this enzyme in the replication of these viruses has been scrutinized, with particular emphasis on potential roles for dUTPase in virulence and viral mutation rate. Overall, the results of these studies have indicated a...
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