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Article

Differential expression of the c‐<i>kit</i> proto‐oncogene in germ cell tumours

1 Nov 1995

Abstract excerpt

The c-kit proto-oncogene product and its ligand stem cell factor play an important role in haematopoiesis, spermatogenesis, and melanogenesis. Using an anti-c-kit antiserum raised against a synthetic peptide, we studied the immunohistochemical expression of the c-kit gene product in 60 germ cell tumours (GCTs) (53 testicular, 7 extragonadal), derived from primary GCTs in 45 cases and metastatic tumours in 15...

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PMID: 8551387
DOI: 10.1002/path.1711770307

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