Article
The role of cell adhesion in retinoic acid-induced modulation of chondrocyte phenotype.
The Biochemical journal - 1 Jan 1996
Sanchez M, Arcella A, Pontarelli G, Gionti E
Abstract excerpt
Retinoic acid (RA) treatment of a suspension of quail chondrocytes inhibits the expression of cartilage collagens and induces cell adhesion along with fibronectin expression. We asked whether the RA-induced modulation of the chondrocyte phenotype was dependent on cell adhesion. Prevention of cell adhesion blocks cell growth and many of the effects associated with RA, such as collagen II inhibition, collagen I...
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