Article
Quantitative analysis of the expression of the HLA-DRB genes at the transcriptional level by competitive polymerase chain reaction.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 1996
Vincent R, Louis P, Gongora C, Papa I, Clot J, Eliaou J F
Abstract excerpt
In addition to polymorphism of the peptide-binding site, the density of the MHC class II molecules expressed on the membrane of APC could well play a significant role in the MHC-peptide-TCR interaction during the immune response. We therefore investigated the regulation of the expression of the HLA-DRB genes at the transcriptional level. A competitive PCR approach was used to estimate the quantities of the...
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