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Article

Association between angiotensin-converting-enzyme gene polymorphism and failure of renoprotective therapy.

Lancet (London, England) - 13 Jan 1996

van Essen G G, Rensma P L, de Zeeuw D, Sluiter W J, Scheffer H, Apperloo A J, de Jong P E

Abstract excerpt

BACKGROUND: Polymorphism in the gene for angiotensin-converting enzyme (ACE), especially the DD genotype, is associated with risk for cardiovascular disease. Glomerulosclerosis has similarities to atherosclerosis, and we looked at ACE gene polymorphism in patients with kidney disease who were in a trial of long-term therapy with an ACE inhibitor or a beta-blocker. METHODS: 81 patients with non-diabetic renal...

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Share to Adrenergic beta-Antagonists
Share to Angiotensin-Converting Enzyme Inhibitors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8538349
DOI: 10.1016/s0140-6736(96)90213-5

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Association between angiotensin-converting-enzyme gene polymorphism and failure of renoprotective therapy.PMID 8538349Read ↗

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