Article
Association between angiotensin-converting-enzyme gene polymorphism and failure of renoprotective therapy.
Lancet (London, England) - 13 Jan 1996
van Essen G G, Rensma P L, de Zeeuw D, Sluiter W J, Scheffer H, Apperloo A J, de Jong P E
Abstract excerpt
BACKGROUND: Polymorphism in the gene for angiotensin-converting enzyme (ACE), especially the DD genotype, is associated with risk for cardiovascular disease. Glomerulosclerosis has similarities to atherosclerosis, and we looked at ACE gene polymorphism in patients with kidney disease who were in...
Topics
- Adrenergic beta-Antagonists
- Angiotensin-Converting Enzyme Inhibitors
- Atenolol
- Double-Blind Method
- Enalapril
- Female
- Genotype
- Glomerular Filtration Rate
- Humans
- Kidney Diseases
- Male
- Middle Aged
- Peptidyl-Dipeptidase A
- Polymorphism, Genetic