Article
Transient leukemia in a newborn without Down syndrome: case report and review of the literature.
European journal of pediatrics - 1 Dec 2014
Rozen Laurence, Huybrechts Sophie, Dedeken Laurence, Heijmans Catherine, Dessars Barbara, Heimann Pierre, Lambert Frédéric, Noubouossie Denis F, Ferster Alina, Demulder Anne
Abstract excerpt
UNLABELLED: Transient neonatal leukemia occurs almost exclusively in Down syndrome babies. We report here the unusual case of a newborn without Down syndrome who presented neonatal transient leukemia and who achieved spontaneously complete remission. Trisomy 21 and GATA1 mutation were both present in leukemic cells. While close follow-up is advised since true leukemia may develop later, the patient is still in...
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