Article
Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype.
The Journal of experimental medicine - 1 Jul 1991
Post T W, Liszewski M K, Adams E M, Tedja I, Miller E A, Atkinson J P
Abstract excerpt
Membrane cofactor protein (MCP) is a complement regulatory protein that is expressed on human cells and cell lines as two relatively broad species with Mr of 58,000-68,000 and 48,000-56,000. The structure of a previously reported cDNA clone indicated that MCP was a type 1 membrane glycoprotein and a member of the regulators of complement activation gene/protein cluster. However, it did not provide an explanation...
Topics
- Amino Acid Sequence
- Animals
- Antigens, CD
- Base Sequence
- Cell Line
- Cloning, Molecular
- Complement System Proteins
- DNA, Neoplasm
- Exons
- Genomic Library