Article
Extragonadal germ cell tumors: A clinicopathologic study with emphasis on molecular features, clinical outcomes and associated secondary malignancies.
Human pathology - 1 Jun 2024
Abdulfatah Eman, Brown Noah A, Davenport Matthew S, Reichert Zachery R, Camelo-Piragua Sandra, Heider Amer, Huang Tao, Vaishampayan Ulka N, Skala Stephanie L, Montgomery Jeffrey S, Chinnaiyan Arul M, Kaffenberger Samuel D, Bawa Pushpinder, Shao Lina, Mehra Rohit
Abstract excerpt
Extragonadal germ cell tumors (EGCTs) are rare, representing <5% of all germ cell tumors (GCTs). Whilst EGCTs share morphological and immunohistochemical features with their gonadal counterparts, they tend to be more aggressive and are frequently associated with secondary somatic malignancies. The aim of our study was to evaluate the clinical, morphological and immunohistochemical features, and to analyze tumors...
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