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Article

Chorismate mutase and 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase of the methylotrophic actinomycete Amycolatopsis methanolica.

Applied and environmental microbiology - 1 Nov 1995

Euverink G J, Hessels G I, Franke C, Dijkhuizen L

Abstract excerpt

Chorismate mutase (CM) and 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase (DS) are key regulatory enzymes in L-Phe and L-Tyr biosynthesis in Amycolatopsis methanolica. At least two CM proteins, CMIa and CMIb, are required for the single chorismate mutase activity in the wild type. Component CMIa (a homodimeric protein with 16-kDa subunits) was purified to homogeneity (2,717-fold) and kinetically...

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Identifiers

PMID: 8526488
DOI: 10.1128/aem.61.11.3796-3803.1995
PMCID: PMC167681

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