Article
Adrenal-specific transgene expression and derivation of conditionally immortal rat adrenocortical cell lines.
Endocrine research - 1 Jan 2000
Morley S D, Viard I, Parker K L, Mullins J J
Abstract excerpt
Conditional immortalisation of cells is a powerful tool for establishing in vitro models maintaining a differentiated phenotype. We are utilising this approach to derive cell lines that maintain the characteristics of glomerulosa and fasciculata cells of the adrenal cortex. Such cell lines should provide a system in which to study aspects of adrenocortical function that are relevant to hypertension, such as the...
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