Article
Altered collagen and glycosaminoglycan syntheses in familial scleroderma skin fibroblasts.
Dermatology (Basel, Switzerland) - 1 Jan 1995
Tajima S, Yamada H
Abstract excerpt
BACKGROUND: The main clinical symptoms of systemic scleroderma are caused by an accumulation of collagen in the tissues. Familial scleroderma is a very rare disorder in which systemic scleroderma occurs in the members of the same family. OBJECTIVE: To know whether or not the biosynthetic properties of familial scleroderma skin fibroblasts are similar to those of nonfamilial scleroderma fibroblasts, syntheses of...
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