Article
Altered collagen and glycosaminoglycan syntheses in familial scleroderma skin fibroblasts.
Dermatology (Basel, Switzerland) - 1 Jan 1995
Tajima S, Yamada H
Abstract excerpt
BACKGROUND: The main clinical symptoms of systemic scleroderma are caused by an accumulation of collagen in the tissues. Familial scleroderma is a very rare disorder in which systemic scleroderma occurs in the members of the same family. OBJECTIVE: To know whether or not the biosynthetic properti...
Topics
- Adult
- Aged
- Collagen
- Dermatan Sulfate
- Family Health
- Female
- Fibroblasts
- Glycosaminoglycans
- Humans
- Hyaluronic Acid
- Middle Aged
- Phenotype
- RNA, Messenger
- Scleroderma, Systemic
- Skin