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Article

Altered collagen of human pathological fibroblasts impairs the synthesis of fibronectin.

Matrix biology : journal of the International Society for Matrix Biology - 1 Mar 1997

Lebbé C, Font J, Bonaventure J, Pichon J, Wantyghem J, Rossi M, Haentjens G, Cohen-Solal L, Aubery M

Abstract excerpt

Human fibroblasts with mutated type I collagen have marked defective adhesive capacities on exogenous type I collagen and exogenous fibronectin in comparison to normal fibroblasts. This defective cell adhesion could be partly explained by the decreased level of cell surface receptors of the beta 1-integrin family, i.e., the alpha 2 integrin subunit for type I collagen and the alpha 5 integrin subunit for...

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Identifiers

PMID: 9106161
DOI: 10.1016/s0945-053x(97)90023-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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