Article
High frequency of Ki-ras amplification and p53 gene mutations in adenocarcinomas of the human esophagus.
Molecular carcinogenesis - 1 Dec 1995
Galiana C, Lozano J C, Bancel B, Nakazawa H, Yamasaki H
Abstract excerpt
Mutated ras genes have been found to be conspicuously absent from primary tumors of the esophagus, although high expression of ras p21 oncoprotein in some esophageal squamous cell carcinomas and mutations of the Ki- and Ha-ras genes in esophageal carcinoma cell lines have been reported. In this s...
Topics
- Adenocarcinoma
- Base Sequence
- Blotting, Southern
- DNA, Neoplasm
- Esophageal Neoplasms
- Female
- Gene Amplification
- Genes, p53
- Genes, ras
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Prognosis