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Article

Analysis of sequence diversity in the Plasmodium falciparum merozoite surface protein-1 (MSP-1).

Molecular and biochemical parasitology - 1 May 1993

Miller L H, Roberts T, Shahabuddin M, McCutchan T F

Abstract excerpt

Immunization with the first identified Plasmodium falciparum merozoite surface protein (MSP-1) protected monkeys from an otherwise fatal infection. The question of whether the high degree of diversity in MSP-1 among parasite clones will be an impediment to its development as a vaccine candidate needs to be resolved. We have aligned all published sequences, identifying errors, resequencing a portion of one...

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PMID: 8515771
DOI: 10.1016/0166-6851(93)90002-f

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