Article
A new model for the origins of allelic dimorphism in Plasmodium falciparum.
Parasitology international - 1 Jun 2015
Roy Scott W, Ferreira Marcelo U
Abstract excerpt
In his landmark 1987 study of the merozoite surface protein-1 locus in Plasmodium falciparum, Kazuyuki Tanabe and coauthors introduced the phenomenon of allelic dimorphism, in which antigenic diversity is arranged into two maximally diverged haplotypes. Further work has extended this finding to other loci in P. falciparum. Each of the loci at which allelic dimorphism is observed encodes major surface antigens of...
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