Article
Missense mutations in the Bacillus subtilis gnt repressor that diminish operator binding ability.
Journal of molecular biology - 20 May 1993
Yoshida K, Fujita Y, Sarai A
Abstract excerpt
The Bacillus subtilis gnt operon is negatively regulated by the gnt repressor (GntR, 243 amino acids), which is antagonized by gluconate. The GntR protein belongs to a new family of bacterial regulatory proteins (GntR family). To locate the DNA-binding domain of the GntR protein, we obtained muta...
Topics
- Amino Acid Sequence
- Bacillus subtilis
- DNA-Binding Proteins
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Molecular Sequence Data
- Multigene Family
- Mutation
- Operator Regions, Genetic
- Repressor Proteins
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid
- Transcription Factors