Article
Transposon mutations in the 5' end of glnD, the gene for a nitrogen regulatory sensor, that suppress the osmosensitive phenotype caused by otsBA lesions in Escherichia coli.
Journal of bacteriology - 1 Jun 2006
Tøndervik Anne, Torgersen Haakon R, Botnmark Hans K, Strøm Arne R
Abstract excerpt
GlnD of Escherichia coli is a bifunctional signal-transducing enzyme (102.4 kDa) which uridylylates the allosteric regulatory protein PII and deuridylylates PII-UMP in response to growth with nitrogen excess or limitation, respectively. GlnD catalyzes these reactions in response to high or low levels of cytoplasmic glutamine, respectively, and indirectly directs the expression of nitrogen-regulated genes, e.g.,...
Topics
- Alleles
- Culture Media
- DNA Transposable Elements
- Down-Regulation
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Glucosyltransferases
- Multigene Family
